UKRAINS'KYI VISNYK PSYKHONEVROLOHII

The Scientific and Practical Journal of Medicine
ISSN 2079-0325(p)
DOI 10.36927/2079-0325
Home » Archive of numbers » 2018 » Volume 26, issue 2 (95) » Monitoring of cellular beta-adrenergic receptors in treatment of patients with early- and middle-stage hypertensive encephalopathy

Monitoring of cellular beta-adrenergic receptors in treatment of patients with early- and middle-stage hypertensive encephalopathy

Authors

Type of Article

  • Scientific Article

In the Section

  • DIAGNOSTICS AND THERAPY OF MENTAL AND BEHAVIORAL DISORDERS

Key words

Index UDK:
  • 616.831-005.4-085.2/.3:[615.036.8 + 612.085.2]

Abstract

The paper deals with the results of the study on cellular beta-adrenergic receptors in patients with chronic cerebral ischemia of hypertensive genesis (hypertensive ence phalopathy) during drug therapy. The goal was to study the relationship of cerebrovascular disorders with the individual characteristics of the stress system. To estimate the beta-adrenergic receptors activity the osmotic fragility test (beta-ARM index of erythrocytes’ membrane upon beta-blocker exposure) has been used. Analyzing the data obtained in the study of patients with hypertensive encephalopathy (n = 81) and controls (n = 33) consisted in within- and between-group comparison of the indices obtained thrice during 2 months at diff erent stages of treatment. The obtained results showed that beta-APM indices allow to differentiate various stages of the disease at the cellular level, depend on the physiological state and sex of patients, and can serve as an objective therapeuticprognostic criterion for evaluating the treatment effi ciency, thus allow optimizing approaches to prevent the development of cerebrovascular disorders

Pages

  • 33-36

Year / Issue

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UKRAINS'KYI VISNYK PSYKHONEVROLOHII

The Scientific and Practical Journal of Medicine

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