The aim of the work is to find predictors of resistance of patients with stress-associated disorders to standard inpatient treatment

Twice (at the beginning and end of inpatient treatment) using the Spielberger-Khanin test, Hospital Anxiety and Depression Scale (HADS), Alcohol Use Disorders Identification Test (AUDIT), as well as methods for assessing the quality of life (for Mezzich), 115 people with complaints of various consequences of traumatic events related to participation in combat or being in a combat zone (including military personnel — 58 people (all men)), with the following diagnoses at the time of hospitalization: adjustment disorders (F 43.2) — 44 people; post-traumatic stress disorder (F 43.1) — 36 people; anxietyphobic disorders (F40.0) — 20 people and anxiety disorders (F41) — 15 people. The obtained data were processed by mathematical statistical methods (variance and correlation analyses) on a computer using Excel 2016 spreadsheets (with the Data Analysis package).

It was found that the most valid criterion for assessing therapeutic resistance of patients with stress-associated disorders is the degree of decrease in the severity of affective symptoms during treatment with a threshold value of such reduction of 10 % of the initial level of anxiety assessed by the corresponding subscale of HADS. The use of this criterion made it possible to divide the examined patients into two unequal groups: resistant (reduction in anxiety ≤10 % of the initial level) and with a positive response to treatment (reduction in anxiety >10 % of its initial level). Comparison of the frequencies of the studied features in these groups made it possible to create a prognostic table of 13 predictors of therapeutic resistance. The nature of the identified predictors indicates that the most important combined factor of resistance to therapy in the examined patients is the somatic status burdened with various troubles. A table has been created for predicting the resistance of patients with stress-associated disorders to standard inpatient therapy with levels of sensitivity, specificity and accuracy (95.5 %, 97.4 % and 92.8 % respectively) sufficient for its practical use.