In the course of this work, aimed at developing and testing psychoeducational interventions in personalized therapy of depressive disorders in persons affected by combat actions, a comprehensive clinical-psychopathological and psychodiagnostic examination of 148 patients with depressive disorders was conducted. Group I included 83 residents of frontline territories, Group II consisted of 65 internally displaced persons. A personalized therapy system was developed and tested using psychopharmacotherapy and personalized gender-differentiated psychotherapeutic and psychoeducational interventions adapted to the specific needs of persons affected by combat actions.

It was established that personalized psychoeducational interventions demonstrate high effectiveness in the comprehensive therapy of depressive disorders in combat-affected individuals. The gender-differentiated approach, taking into account the specificity of traumatic experience, provides 1.6—2.2 times higher effectiveness compared to standard treatment and contributes to significant improvement in patients’ quality of life.