UKRAINS'KYI VISNYK PSYKHONEVROLOHII

The Scientific and Practical Journal of Medicine
ISSN 2079-0325(p)
DOI 10.36927/2079-0325
Home » Archive of numbers » 2024 » Volume 32, issue 4 (121) » FEATURES OF CHANGES IN THE STRUCTURE OF THE VASCULAR WALL IN YOUNG PERSONS WITH ARTERIAL HYPERTENSION

FEATURES OF CHANGES IN THE STRUCTURE OF THE VASCULAR WALL IN YOUNG PERSONS WITH ARTERIAL HYPERTENSION

Authors

Type of Article

  • Scientific Article

In the Section

  • MECHANISMS OF FORMATION AND MODERN PRINCIPLES OF TREATMENT OF NEUROLOGICAL DISORDERS

Key words

Index UDK:
  • 616.12-008.331.1:616-053.6

Abstract

Arterial hypertension (AH) is one of the key risk factors for cardiovascular diseases. In youngpatients with AH, significant changes in the structure of the vascular wall are observed, including endothelial dysfunction, thickening of the intima-media complex of the carotid arteries,and increased arterial stiffness. A comprehensive study was conducted, which included ultrasound assessment of the vascular wall, determination of markers of endothelial dysfunction(endothelin-1, interleukin-6), and inflammation indicators. The obtained data indicate a significant impact of prolonged elevated blood pressure on the development of vascular remodelingand the formation of atherosclerotic changes, which contribute to the risk of chronic brainischemia in young patients with AH.

Pages

  • 59-63

Year / Issue

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References

  1. World Health Organization. Hypertension. URI: https://www.who.int/news-room/fact-sheets/detail/hypertension.
  2. Bilovol, O.M., Kniazkova, I.I., Nesen, A.O., Mazii, V.V., & Valentynova, I.A. Likuvannia arterialnoi hipertenzii u molodykh [Treatment of arterial hypertension in young people]. Liky Ukrainy [Medicines of Ukraine], 2019. 4(230): 30-35. (In Ukrainian) DOI: https://doi.org/10.37987/1997- 9894.2019.4(230).185616.
  3. Kovalenko O. Ie., Havryshchuk B. H. Khronichni tserebrovaskuliarni rozlady u osib molodoho viku: kliniko-diahnostychni, etiopatohenetychni ta likuvalno-profilaktychni aspekty [Chronic cerebrovascular disorders in young people: clinical-diagnostic, etiopathogenetic and therapeutic prophylactic aspects.]. Klinichna ta profilaktychna medytsyna [Clinical and preventive medicine]. 2020;4(14):97-104. (In Ukrainian) DOI: https://doi.org/10.31612/2616-4868.4(14).2020.09.
  4. Ministry of Health of Ukraine. Hypertension: precautions and prevention. (In Ukrainian). https://moz.gov.ua/uk/arterialna-gipertenzija-zapobigannja-ta-profilaktika.
  5. Mishchenko T. S., Bokatuieva V. V., Mishchenko V. M., Kharina K. V. (2022). Osoblyvosti strukturnykh zmin holovnoho mozku u khvorykh molodoho viku z arterialnoiu hipertenziieiu [Peculiarities of brain structural changes in young patients with arterial hypertension]. Psykhiatriia, nevrolohiia ta medychna psykholohiia [Psychiatry, Neurology and Medical Psychology], (20), 12-18. (In Ukrainian). DOI: https://doi.org/10.26565/2312-5675-2022-20-02.
  6. Mishchenko T.S., Mishchenko V.M., Kharina K.V., Linska H.V. Do osoblyvostei likuvannia khronichnoi ishemii mozku u khvorykh molodoho viku z arterialnoiu hipertenziieiu [Features of treatment of chronic cerebral ischemia in young patients with arterial hypertension]. Psykhiatriia, nevrolohiia ta medychna psykholohiia [Psychiatry, Neurology and Medical Psychology]. 2022;19:14–23. doi: https://doi.org/10.26565/2312–5675-2022-19-02.
  7. Wermelt J. A. Management der arteriellen Hypertonie [Management of arterial hypertension] / J. A. Wermelt, H. Schunkert // Herz. 2017. Vol. 42 (5). P. 515—526. German. DOI: https://doi.org/10.1007/ s00059-017-4574-1.
  8. Increased Risk of Hypertension in Young Adults in Southwest China: Impact of the 2017 ACC/AHA High Blood Pressure Guideline / Li D., Zeng X., Huang Y. [et al.] // Curr Hypertens Rep. 2019. Vol. 21 (3). P. 21. DOI: https://doi.org/10.1007/s11906-019-0926-y.
  9. Oros M. Venous discirculation and cognitive impairment / M. Oros & M. Oros Jr // International neurological journal. 2022. Vol. 17(6). P. 43—50. DOI: https://doi.org/10.22141/2224- 0713.17.6.2021.242235.
  10. Dedova, V.O. & Dotsenko, M.Ya & Boyev, S.S. & Shekhunova, I.O. (2014). Pruzhno-elastychni vlastyvosti zahalnykh sonnykh arterii u khvorykh na arterialnu hipertenziiu [Elastic properties of the common carotid arteries in hypertensive patients]. Arterialna hipertenziia [Hypertension]. 20–24. doi: https://doi.org/10.22141/2224-1485.1.33.2014.82662.
  11. Sidelkovskyi O. L., Ovsiannikov O. A., Marusichenko V. V., Savchuk M. M. Diahnostychni shkaly i testy v nevrolohii, neirokhirurhii i neiroreabilitatsii [Diagnostic scales and tests in neurology, neurosurgery and neurorehabilitation]. Kyiv, 2022. 296 p.

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UKRAINS'KYI VISNYK PSYKHONEVROLOHII

The Scientific and Practical Journal of Medicine

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