The purpose of the work is to study the spectrum and severity of psychopathological symptoms, to create, in the future, personalized approaches to the management of trichological patients with mental health disorders associated with alopecia. 153 women aged 25 to 45 with diffuse alopecia were surveyed: without signs of mental maladaptation (MM), 45 people, with separate signs of maladaptation, 73 persons, and with the presence of adaptation disorders according to the ICD-10 criteria, 35 persons. Within each of these groups, two subgroups, considering the genesis of alopecia were distinguished: metabolic (45 patients) or mixed (108 patients). Almost half of people with diffuse alopecia (47.7 %) have some symptoms of psychopathological spectrum, among others — the number of mentally healthy persons and respondents with adaptation disorders F43.2 is approximately the same (29.4 % and 22.9 %, respectively). Among patients with mixed alopecia, the majority (59.3 %) have symptoms at the level of PD, and more than a quarter 28.8 %) — nosologically defined adaptation disorders, while among patients with metabolic alopecia, most (66.7 %) are mentally healthy, 20.0 % have signs of PD and 13.3 % suffer from adaptation disorders. Persons with diffuse alopecia have almost the entire spectrum of psychopathological symptoms, except for significant manifestations of paranoid and psychoticism. The severity of all other manifestations — somatization, obsessive-compulsive disorders, interpersonal sensitivity, depression, anxiety, hostility, phobic anxiety — significantly differs depending on the genesis of diffuse alopecia, demonstrating the general trend of greater expressiveness in patients with a mixed form of alopecia, against patients with metabolic alopecia. Clinical filling and severity of the entire spectrum of psychopathological symptoms is more significant in patients with mixed alopecia (with a natural increase in the severity of all studied psychopathological manifestations in simultaneously with the increase in the severity of MM) than in patients with its metabolic form. The integral indicators of severity and number of psychopathological symptoms, and the severity of symptomatic distress are also significant in persons with mixed alopecia The identified patterns should be considered when constructing a strategy of personalized curation of patients with diffuse alopecia