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In the Section
Abstract
The purpose of the study: on the basis of complex clinical-psychopathological, clinical-anamnestic and psychometric studies of patients with the first diagnosed mental disorders who suffered from the coronavirus disease COVID-19 and were exposed to the stressors of the SARS-CoV-2 pandemic, to determine the clinical and anamnestic correlates of the development of various variants of mental disorders pathologies
To implement the research purpose, 97 patients with the first diagnosed mental disorders who suffered from COVID-19 and were exposed to the stressors of the SARS-CoV-2 pandemic were examined and formed the main group. The diagnosis was established taking into account the ICD-10 criteria (F32.0—32.2 — 34 patients, F40—45 — 32 patients, F06.3—06.6 — 31 patients). The comparison group included 58 people without mental disorders who suffered from COVID-19 and were exposed to the stressors of the SARS-CoV-2 pandemic
The clinical and anamnestic features of patients with the first diagnosed mental disorders who suffered from COVID-19 and were exposed to the stressors of the SARS-CoV-2 pandemic, which reflect characteristic nosological differences, were determined. It was established that the treatment of COVID-19 in hospital conditions (r = 0.553), the degree of lung damage according to CT-2 computed tomography data (r = 0.549), depressive (r = 0.651) and asthenic (r = 0.568) syndromes are associated with depressive episodes; a single case of COVID-19 disease (r = 0.640), the effect on initial psychopathological manifestations of such stressors of the SARS-COV-2 pandemic as a potentially life-threatening situation of uncertain duration (r = 0.575), and uncertainty related to the impact of the pandemic on family / personal socioeconomic status (r = 0.556), anxiety-phobic (r = 0.640) and somatic-vegetative (r = 0.566) syndromes are associated with the formation of neurotic, stress-related and somatoform disorders; two cases of COVID-19 in the anamnesis (r = 0.549), somatic complications after COVID-19 (r = 0.573), initial psychopathological manifestations in the form of cognitive disorders (r = 0.531) and sleep disorders (r = 0.528) characterize mental disorders organic genesis.
The obtained results testify to the combined mechanism of the influence of pathoplastic and psychogenic factors of the coronavirus disease COVID-19 and the stressors of the SARS-CoV-2 pandemic and the heterogeneity of mental pathology in the context of this influence with certain diagnostic and phenomenological regularities.
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References
The Scientific and Practical Journal of Medicine
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П.В. ВОЛОШИНА
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