The article substantiates the possibilities of an individualized approach to the treatment of neurosis-like enuresis based on the study of the gender characteristics of 90 children at the age from 6 to 17 years, among them 66 boys and 24 girls with various clinical options for enuresis.

The research has proved that the diagnostic algorithm for examining children with neurosis-like enuresis should involve a bladder ultrasound with determination of the residual volume of urine and a bacteriological test of the urine for pathogenic fl ora with an antibiotic sensitivity test. It has been established that the boys predominantly had the hypotonic type of the bladder (57.58 ± 6.13) %, while among the girls the hypertonic type (58.3 ± 7.28) % prevailed.

The author presents a varied approach to the examination and treatment of children with enuresis according to the hypotonic and hypertonic types of the bladder. It allows for the right therapy and increases the effectiveness of patients’ treatment. The application of the specifi c therapy with the drug nitrofuran derivatives is justifi ed, which has proved its high bioavailability, eff ectiveness and safety as a monotherapy for bladder infections. Further, to improve the adaptive function of the bladder, improve microcirculation, and reduce hypoxia of detrusor, patients were prescribed 10 % solution of nicoti noyl gamma-aminobutyric acid in the form of ion-galvanic procedures on the lumbosacral spine.

After treatment, a “hypotonic” type of bladder was diagnosed in 19 % of boys, 21 % of girls. After treatment, the frequency of enuresis episodes per night was signifi cantly reduced. The frequency of enuresis several times a month, twice as often observed in girls. Twice less often, cases of enuresis were observed from once a month to once every 3—6 months.

It is proved that the use of the drug nicotinoyl gamma-aminobutyric acid is effective and promising for the treatment of children with neurosis-like enuresis of the hypotonic type