Aim: to study the prevalence of myasthenia gravis among adults in certain regions of Ukraine, taking into account the type of settlement and place of residence.

The biostatistical, medical-statistical and epidemiological methods was used in the study.

A study of the prevalence of myasthenia gravis in Ukraine was conducted on a sample of ten regions of Ukraine.

757 cases of myasthenia gravis were studied in selected territories, of which 465 (61.43 %) were among urban residents, 292 (38.57 %) were among rural residents. The average annual prevalence of myasthenia gravis was 5.16 (95 % CI — 4.79—5.53) per 100,000 population. An analysis of the prevalence of myasthenia gravis in each region showed that this indicator among rural residents was statistically signifi cantly higher than the prevalence of myasthenia gravis among urban residents in Vinnytsia, Zaporizhzhia and Kirovohrad regions (p 0.05). The highest prevalence of myasthenia gravis in rural residents compared with urban residents was in the Vinnytsia region with an excess of 5.63 times (p < 0.001). The city prevalences of myasthenia in the Dnipropetrovsk (+39.14 %; p = 0.001) and Poltava regions (+35.87 %; p = 0.048) signifi cantly exceeded the average city prevalence of myasthenia gravis in Ukraine. They were signifi cantly lower in Vinnytsia (–75.07 %; p < 0.001), Volyn (–51.49 %; p < 0.001), Ivano-Frankivsk (–42.58 %; p = 0.004) and Chernivtsi (–37.35 %; p = 0.046) regions.

The chances of rural residents to have myasthenia gravis were signifi cantly higher compared to urban residents.

In general, according to the data of mya sthenia gravis prevalence rate in the context of the place of residence, it was proved that living in rural areas is associated with the presence of myasthe nia gravis.