The program for the treatment of nonpsychotic mental disorders (NMD) in patients with rheumatoid arthritis (RA) are described in the article. The complex program of treatment for NMD with the use of psychopharmacotherapy and psychotherapeutic approaches (rational psychotherapy, autogenous training, cognitive-behavioral and gestalt therapy) was developed taking into account the revealed specifi city of clinical-psychopathological manifestations, psychopathological features of comorbid non-psychotic mental disorders in patients with RA.

The fi rst group included 51 patients, who, in addition to standard treatment, received only psychopharmacological treatment of NPR (ВGТ I), and the second group — 69 patients receiving complex psychopharmacological and psycho therapeutic treatment (ВGТ II). As evidence shows, the level of depression significantly decreased in the ВGТ II at 11.7 points compared with ВGТ I at 8.1 points. The level of anxiety decreased in ВGТ II at 13.1 points, and in ВGТ I at 8.4 points. The overall assessment of quality of life in ВGТ I, improved by 10.2 points, while ВGТ II — by 15.9 points and the positive eff ect was probable.