The article is devoted to the study of stress resistance, the stress of the forming factors contributing to the emergence and chronicization of pain syndrome, the formation of painful behavior in patients with dorsalgia in various variants of neurological pathology. To study the stress-resistance and adaptive potential of the individual, the scale of social adaptation of Holmes and Ray was used in 65 young patients with chronic back pain (dorsalgia) and neurological pathology represented by multiple sclerosis, persistent neuroinfections and vertebroneurological pathology. When interpreting the results, clinical and anamnestic data were also taken into account. The study confi rmed the role of stress and social maladaptation in the pathogenesis of pain syndromes. There is a signifi - cant stress forming the role of neurological pathology, especially in the onset of neurological disease, when the social maladjustment of the individual is the most signifi cant. It is proved that the rates of development of the neurological disease, its features, personal and social signifi cance can signifi cantly infl uence the formation and further course of dorsalgia, determine the adaptive or disadaptive direction of pain behavior.