UKRAINS'KYI VISNYK PSYKHONEVROLOHII

The Scientific and Practical Journal of Medicine
ISSN 2079-0325(p)
DOI 10.36927/2079-0325
Home » Archive of numbers » 2018 » Volume 26, issue 1 (94) » Features of manifestation of some non-motor phenomena of Parkinson's disease on the background of levodopa therapy

Features of manifestation of some non-motor phenomena of Parkinson's disease on the background of levodopa therapy

Authors

Type of Article

  • Scientific Article

In the Section

  • DIAGNOSIS AND TREATMENT OF NEUROLOGICAL DISORDERS

Key words

Index UDK:
  • 616.858-008.6-071.1-06:615.21

Abstract

In the late stages of Parkinson's disease there are a number of complications associated with prolonged therapy with levodopa. The aim of this observation was to investigate the eff ect of levodopa therapy on the dynamics of non-motor phenomena of Parkinson's disease. It is established that in the late stages of Parkinson's disease non-motor manifestations contribute to the deterioration of the quality of life and the irrational intake therapeutic medicines, in particular levodopa. Therefore, it is important to timely determine the need for levodopa therapy and to monitor the use of levodopa preparations.

Pages

  • 20-23

Year / Issue

Download PDF

References

  1. Parkinson's disease / [G. N. Kryzhanovsky, I. N. Karaban, S. V. Magayeva et al.]. - Moscow: Medicine, 2002. - 335 с.
  2. Moskovko S. P., Moskovko G. С. The world of Parkinson's disease. Kiev : [b. i.], 2007. 30 с.
  3. Motor and non-motor manifestations of Parkinson's disease: pathogenesis and directions of correction / Moskovko SP, Kalishchuk-Slobodin TN, Bogdanova IV [et al]: based on the materials of the II International Congress on Parkinson's Disease (Glasgow, Scotland) // Neuro News Psychoneurology and Neuropsychiatry. 2010. № 7 (26). С. 30-35.
  4. Golubev, V. L. Complications of therapy in late stages of Parkinson's disease and possible approaches to their correction / V. L. Golubev // Journal of Neurology and Psychiatry. С. С. Korsakov. - 2002. - Т. 102, № 4. - С. 52-56.
  5. Naveed M., Donald G. Enhancing dopamine treatments: worth the effort? // Neurodegenerative Disease Management. 2012. Vol. 2, № 4. Р. 365—373.
  6. Bogdanova I. V. Problematic aspects of levodopatherapy at the present stage // Experimental and clinical medicine. 2011. № 3 (52). С. 127-132.
  7. Lees A. J., Hardy J., Revesz Т. Parkinson’s disease  // Lancet. 2009. Vol. 373. P. 2055—2066.
  8. Illarioshkin, S. N. Genetic aspects of Parkinson's disease / [S. N. Illarioshkin, T. B. Zagorevskaya, I. A. Ivanova-Smolenskaya, E. D. Markova] // Neurologicheskiy zhurnal. - М., 2002. - Т. 7. - № 5. - С. 47-52.
  9. The Parkinson’s Disease Questionnaire (PDQ-39): development and validation of a Parkinson’s disease summary index score / С. Jenkinson, R. Fitzpatrick, V. Peto [et al.] // Age and Ageing. 1997. Vol. 26 (5). P. 353—357.
  10. Peto V., Jenkinson C., Fitzpatrick R. Determining minimally important differences for the PDQ-39 Parkinson’s disease questionnaire // Ibid. 2001. Vol. 30. P. 299—302.
  11. Slobodin T. M. Clinical and pathogenetic aspects of emotional and cognitive disorders in Parkinson's disease: PhD thesis ... Doctor of Medicine: specialty 14.01.15 "Nervous diseases". Kharkiv, 2011. 44 с.
  12. Levin O. C., Smolentseva I. G., Ivanov A. K. Non-motor fluctuations in Parkinson's disease // Journal of Neurology and Psychiatry. С. С. Korsakov. 2010. № 3. С. 90-96.
  13. Ivanov A. K. Nemotor fluctuations in Parkinson's disease : diss. ... candidate of medical sciences : specialty. 14.01.11 (14.00.13) "Nervous diseases". Moscow, 2010. 128 с.
  14. Yakovleva LA, Zalyalova Z. A. Pain syndrome in the structure of non-motor manifestations of Parkinson's disease // Neurological Bulletin. 2009. VOL. XLI. С. 64-68.
  15. Identification of motor and nonmotor wearing-off in Parkinson’s disease: сomparison of a patient questionnaire versus a clinician assessment / M. Stacy, A. Bowron, M. Guttman [et al.]  // MovDis. 2005. Vol. 20. P. 726—733.
  16. Maruta, N.A. The concept of the universal role of the paroxysmal brain in the mechanisms of transient states in neurotic disorders / N.A. Maruta, S.P. Kolyadko, T.M. Vorobieva // Bulletin of Psychiatry and Psychopharmacotherapy. - 2006. - No. 1 (9). - P. 10-13.

Journal’s Indexing:

UKRAINS'KYI VISNYK PSYKHONEVROLOHII

The Scientific and Practical Journal of Medicine

ДУ «ІНПН імені
П.В. ВОЛОШИНА
НАМН УКРАЇНИ»