We used the Magnetic resonance imaging (MRI) technique to study the dynamics of structural changes of brain in 32 patients with hepatocerebral degeneration. We have verified that structural changes in the brain of patients with HCD exhibit a diff use character with a predominantly bilateral lesion of subcortical nodes and brainstem gray matter. The white matter of brain was affected to a lesser extent. All patients, in the phase of neurological manifestation of disease, had diff erent severity of atrophic brain processes.

MRI allows to improve the accuracy of HCD diagnosis, to determine the time of the disease conversion to neurological phase and to evaluate the eff ectiveness of chelation therapy.