Complex clinical-anamnestic, neuroimaging and patopsychological examination of 73 patients with vascular dementia was performed. Among them, the main group with high suicide risk (39 patients) and without suicidal behavior — control group (34 patients) were identifi ed. In patients of the main group, there were signs of leukoareosis, atrophy bends of brain and cerebellum, expansion of subarachnoid space. The following risk factors for suicide in patients with vascular dementia are established: psychotraumatic (life-threatening illness, changes in the socio-financial status of the patient, in the life or in the environment of the patient); communicative (lack of emotional support from family and friends, internal orientation of communication and lack of caring for the patient); anamnestic (suicidal attempts and depressive episodes in the past); personal (physical and indirect aggression, touchiness and irritability); clinical (depressive syndrome, emotional instability, hallucinatory-paranoid syndrome).