The study evaluates the eff ectiveness of the use of the drug Neuromidin® (Olainfarm, Latvia) in the complex treatment of patients operated on the lumbar intervertebral disc herniation. The results of the study showed that the appointment of the drug Neuromidin as a drug of choice in patients with degenerative diseases of the spine, especially in the presence of compression of the nervous structures, in particular, the hernia of the intervertebral disc, is pathogenetically grounded in the preoperative and postoperative periods. With course use in patients, Neuromidin has an analgesic eff ect, reducing the severity of back pain and radicular pain. The Neuromidin drug improves neuromuscular transmission, restores pulse activity in the structures of the peripheral nervous system.