Development and estimation of the additional going is conducted near treatment of Parkinson’s disease depending on the degree of weight, which is based on the correction of violations of the functional state of organism. At the ground of the complex program attention was spared by the corrections of violations of oxidant-antioxidant homoeostasis, structurally functional and physical and chemical properties of membranes, functional activity of endocrine, mediator and immune adjusting of metabolic processes. The results testify that, both on the initial stages of forming of neurodegenerative process, when a patient does not yet have a requirement in levodopatherapy and in the cases of the unfolded stages of Parkinson’s disease, expedient are measures which promote adaptation possibilities of organism. One of directions, making better adaptation possibilities of organism of patients, is rational application of complex of preparations, able to be instrumental in support of cells homoeostasis (enfi sol, espalipon (berlition), mexidol, entrope, cardonat, magnerot).