UKRAINS'KYI VISNYK PSYKHONEVROLOHII

The Scientific and Practical Journal of Medicine
ISSN 2079-0325(p)
DOI 10.36927/2079-0325
Home » Archive of numbers » 2009 » Volume 17, issue 4 (61) » Thermal tau-protein — as the marker of axonal damage of cerebrum

Thermal tau-protein — as the marker of axonal damage of cerebrum

Authors

Type of Article

  • Scientific Article

In the Section

  • DIAGNOSIS AND TREATMENT OF NEUROLOGICAL DISORDERS

Key words

Index UDK:
  • 616.8-092.9-071-08:612.015.348

Abstract

In the work it was stated the modern point of view to the problem of adequate diagnostics of axonal damage of cerebrum at the patients with multiple sclerosis and posttraumatic epilepsy. It was showed that the abnormally high level of tau-protein is the real marker of the axonal damage of head and spinal brain and that can be used for monitoring of the results of the therapy and improve the quality of making the prognosis of the course and the outcome of disease

Pages

  • 4-5

Year / Issue

Download PDF

References

  1. Hirano, A. Neurons Astocytes // Textbook of Neuropathology / A. Hirano; Eds. Davis R. Robertson D. — Williams and Wilkins, 1997. — P. 1—109.
  2. Role of Tay-protein in both Physiological and pathological conditions / Avila J., Lucas J. J., Mar Rez, Hernjndes F. // Physiol. Rev. 2004. — Vol. 84 — P. 361—384.
  3. Nod-like protein in inflammation and disease / Carnerio L., Magalhes J., Tattoli I., Philpot D., Travassos L. // J. Pathol. — 2008. — № 214. — P. 136—148.
  4. Cleveland, D. Purification of tau, a microtubule-associated pro tein that induces of microtubules from purified tubulin / D. Cleveland, Y. Hwo, M. Kirschnel // J. Mol. Biol. — 1977. — Vol. 116. — P. 207—225.
  5. Daniels, M. The role of microtubules in the growth and stabilization of nerve fibers / M. Daniels // Ann. Acad. Sci. — 1975. — Vol. 253. — P. 535—544.
  6. Brandt, R. The tau proteins in neuronal growth and development / R. Brandt // Bioscience. — 1996. — P. 118—130.
  7. Drubin, D. Tau protein function in living cells // D. Drubin, M. Kirschner / J. Cell Biol. — 1986. — Vol. 103. — P. 2739—2746.
  8. Goedert, M. Molecular characterization of microtubule-associated proteins tau and MAP2 / M. Goedert, R. A. Crowther, C. C. Garner // Trends Neurosci. — 1991. — № 14(5). — P. 193—199.
  9. Higuchi, M. Tau protein and taupathy. Chapter’ in the book Tau po sitive filamentous lesions in neurodegenerative diseases / M. Higuchi, J. Troja nowski, V. T. Lee. — 2000. — 332 p.
  10. Rober, H. M. Microtubule-associated protein tau as a therapeutic in neurodegeneration / H. M. Rober, M. L. Hutton // Expert Opin. Ther. Targets. — 2007. — № 11 (4). — P. 435—442.
  11. Rademarers, R. The role of tau (MAPT) in frontotemporal dementia and related tauopathies / R. Rademarers, M. Cruts, C. van Broeckhoven // Hum. Mutat. — 2005. — № 24 (4). — P. 277—295.
  12. Rapid tau protein dephosphorylation and differential rephosphorylation during cardiac arrest-indysed cerebral ischemia and reperfusion / C. Mailliot, V. Dimster, R. Rosentha [et al.] // Journal of Cerebral Blood &Metabolism. — 2000. — № 20. — P. 543—549.
  13. Cellular phosporylation of tau by GSK influences tau binding to microtubules to microtubules and microtubule organization / Wagner U., Uttoni M., Gallo J., Miller C. // J. of Cell Science. — 1996. — № 109. — P. 1537—1543.
  14. Voloshina, N. P. Clinical neurophysiology of autoimmune demyelinating and neurodegenerative diseases / N. P. Voloshina, O. V. Egorkina, I. K. Gaponov // Materialy nauk.-pract. conf. "Karpatski chitannya". - Uzhgorod, 2008. - С. 34-35
  15. Chowolhury, D. Axonal Guillfin-Barrt Syndrome: a critical review / D. Chowolhury, A. Arora // Acta Neurol. Scand. — 2001. — № 103. — P. 266—277.
  16. Yevtushenko, S. K. Multiple sclerosis in children (clinic, diagnosis, treatment) / S. K. Yevtushenko, M. A. Moskalenko. - Kiev. - 2009. - 254 с.
  17. Zemian, P. F. US Patent & — Method of detecting axonallyderived protein tau in patients with traumatic CNS injury / P. F. Zemian // Traumatic CNS injury. — 2003.

Journal’s Indexing:

UKRAINS'KYI VISNYK PSYKHONEVROLOHII

The Scientific and Practical Journal of Medicine

ДУ «ІНПН імені
П.В. ВОЛОШИНА
НАМН УКРАЇНИ»