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Abstract
This study results the polysomnographic monitoring in 11 primaryprogressive multiple sclerosis patients with restless legs syndrome (RLS).
We identifi ed the objective changes in the functioning of somnogenic brain resulting in a change in the architectonic structure of night’s sleep, sleep phases destabilization, desynchronizing brain systems activation, NREM and REM sleep organizing disorders. We revealed the lesion of switching stages and phases of sleep and its maintaining mechanisms in primaryprogressive multiple sclerosis with restless leg syndrome
In adition to the clinical sings caused by focal brain progressive damage, sleep disorders can be caused by the development of secondary RLS having pathogenic mechanisms associa ted with functional nonspecifi c brain systems involving, which complicates the formation of multiple sclerosis symptoms.
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References
The Scientific and Practical Journal of Medicine
ДУ «ІНПН імені
П.В. ВОЛОШИНА
НАМН УКРАЇНИ»