The aim of the work was to study the dynamics of affective and addictive symptoms, as well as the quality of life in patients with stress-related disorders during standard inpatient treatment.

Twice (at the beginning and end of inpatient treatment) using the Spielberger-Khanin test, Hospital Anxiety and Depression Scale (HADS), Alcohol Use Disorders Identification Test (AUDIT), as well as methods for assessing the quality of life (for Mezzich), 115 people with complaints of various consequences of traumatic events related to participation in combat or being in a combat zone (including military personnel — 58 people (all men)), with the following diagnoses at the time of hospitalization: adjustment disorders (F 43.2) — 44 people; post-traumatic stress disorder (F 43.1) — 36 people; anxietyphobic disorders (F40.0) — 20 people and anxiety disorders (F41) — 15 people. The obtained data were processed by mathematical statistical methods (variance and correlation analyses) on a computer using Excel 2016 spreadsheets (with the Data Analysis package).

It was found that on average during standard inpatient therapy, the severity of situational anxiety and personal anxiety according to the Spielberger-Khanin test decreased by 11.99 ± 2.09 % and 7.91 ± 1.54 %, respectively, and anxiety and depression according to the HADS scale decreased by 28.20 ± 3.17 % and 21.67 ± 3.30 %, respectively. At the same time, the quality of life (according to the Mezzich method) increased by 15.43 ± 3.25 %, and addictive symptoms (the severity of disorders due to alcohol use, assessed using the AUDIT test) did not undergo statistically significant changes.

It was shown that the specialized medical care provided by the current unified clinical Protocol of primary and specialized medical care “Acute stress reaction. Post-traumatic stress disorder. Adaptation disorders” can provide a positive response to therapy in only slightly more than half of patients (51.82—66.04 % depending on the treatment effectiveness criteria used). The conclusion is made about the need to develop and implement innovative treatment methods capable of increasing the effectiveness of the treatment of stress-associated disorders.