This study presents the features of mental disorders associated with war-related stress in combatants undergoing treatment in therapeutic, neurological, and surgical departments of a military hospital. Clinical-psychopathological examination of military personnel during hospitalization allowed for the diagnosis of distinct syndrome complexes in different departments: therapeutic department — anxiety-insomnia, post-traumatic and social-maladaptive syndrome complexes; neurological department — avoidant, depressive-anxious, and insomnia-social syndrome complexes; surgical department — acute traumatic, anxious-depressive, and obsessive-avoidant syndrome complexes.

Based on the data obtained, we developed and tested a comprehensive personalized program of psychotherapeutic and pharmacological support.

As a result of the program, most combatants experienced improved physical health and work capacity (by 36.0% in the therapeutic department, 20.0% in the neurological department, and 18.0 % in the surgical department). A significantly larger proportion of military personnel reported improved mental health, including emotional state and psychological well-being (by 20.9%, 24.6%, and 26.1%, respectively). Sleep quality improved in 78.0% of patients in the therapeutic department, 72.0% in the neurological department and 93.0 % in the surgical department. Upon completion of therapy, all three groups exhibited reduced anxiety levels, decreased severity of depressive symptoms, and a lower intensity of PTSD manifestations.

Thus, the individualization of the therapeutic approach for hospitalized military personnel, taking into account the specifics of their mental disorders within each department, allows for the highest effectiveness of treatment interventions. The implementation of a comprehensive personalized treatment program effectively restores both physical health and psychological stability in combatants, reducing symptoms of anxiety, depression, and PTSD, and facilitating their readiness to return to active duty.

Early and comprehensive treatment of war-related mental disorders in combatants can significantly reduce the societal costs of restoring their mental health both during and after the war.