UKRAINS'KYI VISNYK PSYKHONEVROLOHII

The Scientific and Practical Journal of Medicine
ISSN 2079-0325(p)
DOI 10.36927/2079-0325
Home » Archive of numbers » 2025 » Vol. 33, Issue 1 (122) » COMBINED LIDOCAINE BLOCKADES WITH METHYLPREDNISOLONE IN THERAPY OF SEVERE TRIGEMINAL NEURALGIA: CLINICAL RESULTS

COMBINED LIDOCAINE BLOCKADES WITH METHYLPREDNISOLONE IN THERAPY OF SEVERE TRIGEMINAL NEURALGIA: CLINICAL RESULTS

Authors

Type of Article

  • Scientific Article

In the Section

  • MECHANISMS OF FORMATION AND MODERN PRINCIPLES OF TREATMENT OF NEUROLOGICAL DISORDERS

Key words

Index UDK:
  • 616.833.15-009.7-089

Abstract

Objective. To estimate the efficacy of lidocaine blockades (LB) with methylprednisolone in patients with trigeminal neuralgia (TN) in both short- and long-term perspectives.

The study analyzed the treatment of 44 patients with TN using peripheral nerve blocks: 31 women (70.45%) and 13 men (29.54%); mean age ± sd — 62.50±13.46 years; disease duration — 8.97±9.6 years. The blocks were performed using a mixture of 4.0 ml of 2% lidocaine with 1.00 ml of 40 mg/ml of methylprednisolone acetate («Depo-Medrol») administered paraneurally. Pain intensity was assessed using the Visual Analog Scale (VAS) at various time points: from 30 minutes to three years after the blockades.

Pain intensity at admission ranged from 5.9 to 10 (8.66±1.06) cm on the VAS. Thirty minutes after the block, it decreased to 1.0—4.5 (2.75±0.67). Due to the return of pain, radical surgical interventions were performed in 36 patients. After 36 months, excellent and good results were achieved in 8 (18.18 %) patients.

Lidocaine blockades with methylprednisolone proved their high short-term efficacy with noticeable, however, decrease during first days with further restoration in terms from the first month to 3 years. The use of this approach is advisable as part of the comprehensive treatment of TN patients.

Pages

  • 19-27

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UKRAINS'KYI VISNYK PSYKHONEVROLOHII

The Scientific and Practical Journal of Medicine

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