Taking into account the relevance of the diseases of old age and the consequences of cardiovascular diseases, which are increasing every year, we conducted a study of neuropsychiatric symptoms (NPS) of vascular dementia (VD) and the correlation of these symptoms both within one etiological group of dementia (VD) and in comparison with others groups (neurodegenerative disorders, NDD and mixed dementia, MD).

With the statistical processing of data, a reliable relationship was established and the difference in the course of NPS in patients with VD was determined in relation to psychotic, affective and behavioral clusters of NPS. In the study of psychotic disorders, the highest frequency of delusions of poisoning is found in patients with VD. The study of affective disorders gave an understanding of higher frequency in combination of different manifestations of affective NPS within this cluster (in particular, apathy and anxiety in one patient) and with other clusters (for example, irritability and movement disorders or depression or anxiety and delusional syndrome) in patients with VD than among other etiological groups. Behavioral disorders in patients with VD were characterized by the following differences: wandering in the middle of the night is more common in patients with VD; the use of non-edible products is not as common in VD as in NDD.

The study of neuropsychiatric symptoms in patients with vascular dementia makes it possible to better understand the peculiarities of the course of the pathology, evaluate the possibilities of implementing effective management of these symptoms, and predict their complications to ensure proper adaptation of the medical system, the patient and his caregivers to the challenges that arise when the diagnosis of vascular dementia is established.