UKRAINS'KYI VISNYK PSYKHONEVROLOHII

The Scientific and Practical Journal of Medicine
ISSN 2079-0325(p)
DOI 10.36927/2079-0325
Home » Archive of numbers » 2020 » Volume 28, issue 4 (105) » Psychotic disorders in COVID-19: mechanisms of development, clinical and treatment feature

Psychotic disorders in COVID-19: mechanisms of development, clinical and treatment feature

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Type of Article

  • Scientific Article

In the Section

  • PROBLEMATIC AND REVIEW ARTICLES

Key words

Index UDK:
  • 616.89-02-022:578.834-616-092.11-616.89-02-07

Abstract

The purpose of this review was to study the mechanisms of development, clinical features and treatment of psychotic disorders during the disease caused by the SARS-CoV-2 virus. In the first part of the review, especial attention was paid to the available literature data on the mechanisms of development of mental disorders in COVID-19. Among the main pathogenetic mechanisms of the onset of psychotic disorders in coronavirus infections, there are direct effects of a viral infection (including a brain infection), cerebrovascular diseases, hypoxia, an immunological response, the consequences of medical interventions, social isolation, the psychological impact of a severe and potentially fatal illness, fears of infecting another’s and stigmatization. The second part of the publication is devoted to a review of clinical studies and syndromokinesis in infectious and coronavirus psychoses. Particular attention is paid to delirious syndrome, including pharmacogenic delirium and antibiotic-associated encephalopathy.

The article describes the features of therapy for psychotic disorders in COVID-19, taking into account drug-drug interactions and the effect on the cardiovascular and respiratory systems.

The analyzed literature allows us to make a reasonable conclusion that the management of coronavirus psychoses should be aimed at treating the underlying disease while eliminating psychotic symptoms with antipsychotics while ensuring maximum safety of psychopharmacotherapy.

Pages

  • 14-17

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References

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UKRAINS'KYI VISNYK PSYKHONEVROLOHII

The Scientific and Practical Journal of Medicine

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