The article presents the results of a study of persons who filed somatic complaints to a general practitioner — family doctor in an outpatient clinic in Kyiv and use alcohol with harmful consequences.

From the standpoint of evidencebased medicine, on the basis of an interdisciplinary approach, biological, psychological and social patterns of the formation of mental and behavioral disorders in persons who have consumed alcohol with harmful consequences have been determined. On this basis, a system of specialized medical care has been scientifically substantiated, developed and implemented, which is a complex of medical, psychological, educational and social measures developed taking into account the influence of biopsychosocial factors in the genesis of mental and behavioral disorders and aimed at preventing or eliminating clinical and psychopathological symptoms, reduction or refusal of respondents from using alcohol with harmful consequences and thereby improving their somatic state, reducing sick leave, ensuring a decent level of social functioning in everyday life. The specified system includes a combination of psychopharmacotherapeutic influences, differentiated depending on the clinical specifics of mental and behavioral disorders and types of personal and behavioral responses. The introduction of this system in health care institutions and specialized universities has proven its effectiveness in reducing clinical and psychopathological manifestations, as well as changes in the social functioning and quality of life of patients.