Early identification of violations of night breathing disorder in patients with motor neuron disease (MND) will allow to choose the correct medical tactics and to increase quality of life of the patient.

Aim: to establish features of night breathing disorder in MND patients, to ana lyse diff erences between male and female, diff erent forms of a disease.

44 MND patients aged from 38 up to 79 years, from them 25 (56.8 %) women and 19 (43.2 %) men have been investigated. 41 persons have entered into control group. The analysis of parameters of a dream it was carried out on the equipment Somno-lab2 Weinnman (Germany) to Laboratories of the Sleep Laboratory of the SE "Republican Clinical Medical Center" of the Administration of the President of Republic of Belarus.

The expressed violations of a sleep architecture of the MND patients in the form of signifi cant increase arousals, expressed a reduction of the phase S3 of slow N-REM of sleep, shortenings of other stages of a sleep of S2 and S4, a REM sleep are revealed. Sleep breathing disorders are found in MND patients mainly as alveolar hypoventilation syndrome and less frequently as obstructive sleep apnea. Signifi cantly low level minSpO2 is revealed that indicates subclinical development of a syndrome of night hypoventilation and importance of defi nition minSpO2 as early marker of the night breathing disorder

Carrying out the polysomnography is the most informative method of a research allowing to estimate all range of changes of a sleep and respiratory violations, especially, at early stages of a disease in MND patients.