ГоловнаArchive of numbers2016Volume 24, issue 3 (88)Cognitive impairments in patients with bipolar affective disorder (clinical features, diagnosis, therapy)
Title of the article Cognitive impairments in patients with bipolar affective disorder (clinical features, diagnosis, therapy)
Authors Maruta Natalia
Verbenko Georgiy
In the section PROBLEMATIC ARTICLES
Year 2016 Issue Volume 24, issue 3 (88) Pages 5-10
Type of article Scientific article Index UDK 616.895+616.89-008.45/47+616-07-08 Index BBK -
Abstract It was performed an examination of 120 patients with bipolar affective disorder (BAD), including 40 patients (33.3 %) with predomination of depressive symptoms (F31.3—5, F31.6) (BAD-D), 30 patients (25.0 %) with predomination of maniacal symptoms (F31.0—2, F31.6) (BAD-M), and 50 patients (41.7 %) in euthymic period (F31.7) (BAD-E). It was determined that cognitive impairments in BAD were manifested as a wide range of psychopathological phenomena which were more prevalent in patients with BAD-M and BAD-D and were less prevalent in patients with BAD-E. Peculiarities of the BAD phenomenological structure for diff erent phases of the disease were detected. Patients with BAD-M had such manifestations of cognitive impairments as a increased selfesteem (56.7 %) and speed of thoughts (86.7 %), an exaggeration of their achievements and abilities (73.3 %), impairments of executive functions, fi rst of all, in problems with a decision making (83.3 %). In patients with BAD-D cognitive impairments were registered as rigidity of thinking (52.5 %), impairments with concentration (95.0 %) and executive functions (planning and decision making) (85.0 %). Patients with BAD-E had impairments of concentration (64.0 %), decreased executive functions (planning and decision making) (46.0 %), decreased levels of interests and critics regarding attitude to the disease (38.0 %). Peculiarities of cognitive impairments in diff erent BAD phases were important criteria for diagnosis of this pathology and should be taken into account in therapeutic processes and rehabilitation of such patients. A consideration of characteristics of cognitive functioning depending on BAD phase allows improving effi cacy of treatment for this category of patients.
Key words bipolar aff ective disorder, cognitive impairments, phase of the disorder, diagnosis, therapy
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Bibliography 1. Александров, А. А. Биполярное аффективное рас ст ройство: диагностика, клиника, течение болезни [Текст] / А. А. Алек- сандров // Медицинские новости. — 2007. — №12. — C. 7—12. 2. Кожина, А. М. Современные стратегии в терапии бипо- лярного аффективного рас ст ройства [Текст] / А. М. Кожина, Л. М. Гайчук // Психічне здоров’я. — 2009. — T. 3—4 (24—25). — C. 60—62. 3. Марута, Н. А. Биполярные рас ст ройства: распространен- ность, медико-социальные последствия, проблемы диагностики [Электронный ресурс] / Н. А. Марута // Нейро News. — 2011. — № 2 (29). — Режим доступа : http://www.neuro.health-ua.com/ article/439.html. 4. Очеретяная, Н. Биполярное рас ст ройство: клини чес кий обзор [Текст] / Н. Очеретяная // Здоров’я України. — 2011. — № 4 (19). — С. 36—37. 5. Хаустова, Е. А. Современные аспекты диагностики и лечения биполярной депрессии [Текст] / Е. А. Хаустова, В. Г. Безшейко, А. П. Романив // Нейро News. — 2012. — №1(36). — С. 38—42. 6. Стан психічного здоров’я населення та перспективи роз- витку психіатричної допомоги в Україні [Текст] / М. К. Хобзей, П. В. Волошин, Н. О. Марута та ін. // Український вісник психо- неврології. — 2012. — Т. 20, вип. 3. — С. 13—18. 7. Чабан, О. С. Биполярная депрессия: проблемы диагностики и терапии [Текст] / О. С. Чабан, Е. А. Хаустова // Нейро News. — 2011. — №5(32). — С. 18—22. 8. Is unrecognized bipolar disorder a frequent contributor to apparent treatment resistant depression [Text] / R. Correa, H. Akiskal, W. Gilmer et al. // J. Affect. Disord. — 2010. — V. 127. — P. 10—18. 9. Trotta, A. Do premorbid and post-onset cognitive functioning differ between schizophrenia and bipolar disorder? A systematic review and meta-analysis [Text] / A. Trotta, R. M. Murray, J. H. MacCabe // Psychol. Med. — 2014. — Vol. 1. — P. 1—14. 10. A systematic review of the evidence of the burden of bipolar disorder in Europe [Electronic Resource] / L. Fajutrao, J. Locklear, J. Priaulx, A. Heyes // Clin. Pract. Epidemiol. Ment. Health. — 2009. — Vol. 5. — P.: 3. Available at. — Mode of access : URL : http://www. ncbi.nlm.nih.gov/ pmc/articles/PMC2646705/ 11. Cognition and functioning in bipolar depression [Text] / N. S. Kapczinski, J. C. Narvaez, P. V. Magalhães et al. // Rev. Bras. Psiquiatr. — 2016. — Feb 5. — doi:10.1590/1516-4446-2014-1558 12. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010 [Text] / R. Lozano, M. Naghavi, K. Foreman, et al. // The Lancet. — 2013. — Т. 380. — № 9859. — Р. 2095—2128. 13. Robinson, L. J. Evolution of cognitive impairment in bipolar disorder: a systematic review of cross-sectional evidence [Text] / L. J. Robinson, I. N. Ferrier // Bipolar Disorders. — 2006. — Vol. 8. — P. 103—116. 14. Vieta, E. Clinical management and burden of bipolar disorder: results from a multinational longitudinal study (WAVE-bd) [Text] / E. Vieta // International Journal of Neuropsychopharmacology. — 2013. — №16. — P. 1719—1732.