ГоловнаArchive of numbers2013Volume 21, issue 3 (76)Peculiarities of epilepsy pathomorphosis with onset of the disease in childhood and adolescence
Title of the article Peculiarities of epilepsy pathomorphosis with onset of the disease in childhood and adolescence
Authors Maryenko Lidiya
In the section ABSTRACTS OF THE SCIENTIFIC-PRACTICAL CONFERENCE "ACTUAL PROBLEMS OF CHILDHOOD EPILEPTOLOGY", September 5—6, 2013, Kharkiv, Ukraine
Year 2013 Issue Volume 21, issue 3 (76) Pages 109-113
Type of article Scientific article Index UDK 616.853-053.4/.6-02 Index BBK -
Abstract Peculiarities of age-related, clinical and therapeutic pathomorphosis of epilepsy, depending on several factors, were outlined on the basis of сatamnestic data of 326 patients with epilepsy onset in childhood, adolescence and young adulthood. Positive (with respect to health) age-related and therapeutic pathomorphosis of epilepsy was identifi ed in patients with idiopathic epilepsy with development of remission in 84.2 % of patients. Negative age-related and therapeutic pathomorphosis of epilepsy with development of drug-resistance has been ascertained with epilepsy onset at an earlier age; with increasing duration of the disease; after failure of fi rst adequately chosen antiepileptic drug; in symptomatic epilepsy of childhood due to perinatal pathology, cerebral palsy, traumatic brain injury, hippocampal sclerosis, in adolescents — in space-occupying lesions of the brain. Gender of patients and impact of additional exogenous harmful factors upon the disease did not aff ect the outcome and clinical pathomorphosis of epilepsy.
Key words epilepsy, age-related pathomorphosis, therapeutic pathomorphosis, childhood, adolescence.
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Bibliography 1. Евтушенко, С. К. Разрушительные и труднокурабельные формы эпилепсии и эпилептические энцефалопатии у детей / С. К. Евтушенко // Міжнародний неврологічний журнал. — 2012. — № 6 (52). — С. 15—30.
2. Карлов, В. А. Эпилепсия у детей и взрослых женщин и мужчин : руководство для врачей / В. А. Карлов. — М.: Медицина, 2010. — 720 с.
3. Мухин, К. Ю. Эпилептические энцефалопатии и схожие синдромы у детей / К. Ю. Мухин, А. С. Петрухин, А. А. Холин. — М.: Артсервис Лтд, 2011. — 680 с.
4. Отахара, С. Эволюция эпилепсий и эпилептических синдромов / А. С. Петрухин. В кн.: Эпилептология детского возрас- та / А. С. Петрухин, ред. — М.: Медицина, 2000. — С. 238—246.
5. Симптоматические и предположительно симптоматические фокальные эпилепсии с дебютом в детском возрасте: взгляд «взрослого» эпилептолога / [А. С. Котов, И. Г. Рудакова, Ю. А. Бе лова, С. В. Котов] // Русский журнал детской невроло- гии. — 2008. — Т. ІІІ. — Вып. 3. — С. 3—11.
6. A population-based study of long-term outcomes of cryptogenic focal epilepsy in childhood: cryptogenic epilepsy is probably not symptomatic epilepsy / [E. C. Wirrell, B. R. Grossardt, E. L. So, K. C. Nickels] // Epilepsia. — 2011. — 52(4). — P. 738—745.
7. Adult Phenotypes in Angelman- and Rett-Like Syndromes / M. H. Willemsen [et al.] // Mol Syndromol. — 2012. — V. 2 (3—5). — P. 217—234.
8. Baram, T. Z. The brain, seizures and epilepsy throughout life: understanding a moving target / T. Z. Baram // Epilepsy Currents. — 2012. — V. 12. — No. 4 Suppl. — P. 7—12.
9. Course and outcome of childhood epilepsy: a 15-year followup of the Dutch Study of Epilepsy in Childhood / A. Geerts [et al.] // Epilepsia. — 2010. — V. 51 (7). — P. 1189—1197
10. Epidemiology, aetiology, and clinical management of epilepsy in Asia: a systematic review / T. L. Mac [et al.] // Lancet Neurol. — 2007. — V. 6. — P. 533—543.
11. Hellpach, W. Pathomorfozen / W. Hellpach // Med. Welt. — 1929. — No 3. — S. 478—479.
12. Hughes, J. R. Benign epilepsy of childhood with centrotemporal spikes (BECTS): to treat or not to treat, that is the question / J. R. Hughes // Epilepsy Behav. — 2010. — V. 19 (3). — P. 197—203.
13. Is Temporal Lobe Epilepsy with childhood febrile seizures a distinctive entity? A comparative study / K. Heuser [et al.] // Seizure. — 2011. — V. 20(2). — P. 163—166.
14. Long-term prognosis of seizures with onset in childhood / M. Sillanpaa [et al.] // N Engl J Med. — 1998. — V. 338. — P. 1715—1722.
15. Onset of intractability and its course over time: the Dutch study of epilepsy in childhood / A. Geerts [et al.] // Epilepsia. — 2012. — V. 53(4). — P. 741—51.
16. Patterns of treatment response in newly diagnosed epilepsy / M. J. Brodie [et al.] // Neurology. — 2012. — V. 78 (20). — P. 1548—1554.
17. Pullianen, V. Motor and cognitive functions in newly diagnosed adult seizure patients before antiepileptic medication [Text] / V. Pullianen, P. Kuikka, M. Jokelainen // Acta Neurol Scand. — 2000. — V. 101 (2). — P. 73—78.
18. The outcome of childhood epilepsy: what improvements are needed? / P. Camfield [et al.] // Epileptic Disord. — 2013. — V. 5 (2). — P. 101—104.
19. The epidemiology of epilepsy in Europe: a systematic review / Forsgren L. [et al.] // European Journal of Neurology. — 2005. — V. 12. — P. 245—253.