ГоловнаArchive of numbers2020Volume 28, issue 3 (104)Stable complexes of neuropsychiatric symptoms in patients with vascular dementia with different localization of brain pathological focuses
Title of the article Stable complexes of neuropsychiatric symptoms in patients with vascular dementia with different localization of brain pathological focuses
Authors Zlobin Oleksandr
In the section DIAGNOSTICS AND THERAPY OF MENTAL AND NARCOLOGICAL DISORDERS
Year 2020 Issue Volume 28, issue 3 (104) Pages 44-50
Type of article Scientific article Index UDK 616.89-008.454-06:616.831.2]-07 Index BBK -
Abstract DOI: https://doi.org/10.36927/2079-0325-V28-is3-2020-7

 The aim of the study was to determine the stable complexes of neuropsychiatric symptoms inherent in patients with vascular dementia with different localization of brain damage. 157 people with a diagnosis of vascular dementia were examined. Group 1 included 22 people with localization of the pathological process in the frontal lobe, group 2 — 18 patients with lesions of the temporal lobe, group 3 — 17 patients with lesions of the parietal lobe, group 4 — 15 patients with lesions of the occipital lobe, group 5 — 68 people with total defeat. All contingents are post-stroke patients over 50 years old, the average age is 68.12 years. Research methods: clinical-psychopathological, clinical-instrumental, experimental-psychological, anamnestic, clinical-statistical. The stable complexes (clusters) of neuropsychiatric symptoms inherent in patients with vascular dementia with different localization of brain lesions were determined. Revealing the following stable associations “localization — cluster”: frontal lobe — subpsychotic cluster (delusion — hallucinations — euphoria — agitation — depression); temporal lobe — asthenoanxiotic cluster (anxiety — irritability — agitation — sleep disturbances — apathy); parietal lobe — excitable-depressive cluster (depression — agitation — irritability — sleep disturbances); occipital lobe — affectocentric cluster (anxiety — depression — agitation — irritability); total defeat — asthenopathoideatoric cluster (apathy — irritability — agitation — anxiety — delirium). The identification of the association allows one to confidently determine the nature of the expected neuropsychiatric symptoms immediately after obtaining neuroimaging data regarding the localization of the lesion, which creates optimal conditions for the timely formation of a program of appropriate therapeutic interventions.
Key words vascular dementia, psychopathology, affective symptoms, neuropsychiatric symptoms, geriatric psychiatry
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