ГоловнаArchive of numbers2019Volume 27, issue 4 (101)The method of objective assessment of the effectiveness of treatment of patients with depression
Title of the article The method of objective assessment of the effectiveness of treatment of patients with depression
Authors Linska Kateryna
In the section DIAGNOSTICS AND THERAPY OF MENTAL AND NARCOLOGICAL DISORDERS
Year 2019 Issue Volume 27, issue 4 (101) Pages 35-44
Type of article Scientific article Index UDK 616.895.4:612.821.1 Index BBK -
Abstract The purpose of the work is to creation of a method for an objective assessment of the eff ectiveness of therapy for patients with depression. A total of 97 patients with depression (main group), an average age of 40.94 ± 1.25 years (among them 51 peop le diagnosed with a depressive episode (F32 according to ICD-10) and 46 people diagnosed with recurrent depression (F33 according to ICD-10) were examined, as well as 64 practically healthy individuals, with an average age of 41.21 ± 1.21 years (control group). We used clinical-psychopathological, psychometric (computer versions Zung and HADS scales, Spielberger-Khanin and AUDIT tests, and also Derogatis questionnaire), as well as psychophysiological methods. The latter method involved the use of software- hardware complex "Reocom-stress" (manufacturer: "KhAI-Medika", Kharkiv, Ukraine) in the "Attitude to the topic" mode with registration of the psychophysiological response to the groups of questions (thematic groups) contained in the above-mentioned psychometric methods. All the methods described during the study were applied twice, with an interval of 17—19 days. It was shown that the three channels of information used in the study (scale scores in points, reaction time to the presented stimuli, and attitude to the topic) are relatively independent of each other and carry additional information about the mental status of the respondents. It is proved that the chronometric channel of information among others is the most sensitive to changes in the mental status of patients with depression during their treatment. It was established that the hig hest diagnostic properties, in terms of an objective assessment of the eff ectiveness of therapy for patients with depression (sensitivity — 86.60 %, specifi city — 96.88 % and faultlessness — 90.68 %), are inherent in the Zung scale (in its computer version, with the function estimates of the respondent’s response to each question/ statement). Together with the simplicity of implementation, such properties make this method of evaluating the eff ectiveness of therapy quite suitable for practical use.
Key words depression, therapy eff ectiveness, objective assessment, psychophysiological reactions
Access to full text version of the article pdf download
Bibliography


1. World Health Day 2017 — Depression: Let’s talk // Fact sheet — 02/2017. URL : http://www.searo.who.int/entity/world_health_day/2017/en/.
2. Mishyiev V. D. Suchasni depresyvni rozlady. L. : Vyd-vo Ms, 2004. 208 s.
3. Yureva L. N. Klinicheskaya suitsidologiya (monografiya). Dnepropetrovsk : Porogi, 2006. 472 s.
4. Gilbody S., Sheldon T., Wessely S. Should we screen for depression? // BMJ. 2006; 332: 1027—1030. DOI: 10.1136/ bmj.332.7548.1027.
5. Jensen A. R. Clocking the mind: mental chronometry and individual differences. First edition. Amsterdam, The Netherlands : Elsevier, 2006. 272 p.
6. Maruta N. O., Linska K. I. Khronometrychnyi profil khvorykh na depresiiu pry vykorystanni kompiuternoho variantu shkaly Tsunha i yoho diahnostychne znachennia // Ukrainskyi visnyk psykhonevrolohii. 2018. T. 26, vyp. 4 (97). S. 57—65.
7. Maruta N. A., Linskaya E. I. Diagnosticheskoe znachenie vremeni otveta na voprosyi u patsientov s depressiey pri ispolzovanii kompyuternogo varianta shkalyi HADS // Psihiatriya, psihoterapiya i klinicheskaya psihologiya. 2019.-T. 10, # 2. S. 199—215.
8. Linska K. I. Khronometrychnyi profil khvorykh na depresiiu pry vykorystanni testu Spilberhera — Khanina // Ukrainskyi visnyk psykhonevrolohii. 2019. T. 27, vyp. 1 (98). S. 57—65.
9. Linska K. I. Stavlennia do verbalnykh i neverbalnykh zvukovykh stymuliv ta chas reaktsii na nykh yak diahnostychni markery depresii patsiientiv // Medychna psykholohiia. 2019. T. 14, vyp. 1 (53). S. 62—73.
10. Linska K. I. Stavlennia khvorykh na depresii do tem, shcho stosuiutsia yikhnoho psykhichnoho statusu, za rezultatamy psykhofiziolohichnoho doslidzhennia // Tam samo. 2019. T. 14, vyp. 3 (55). S. 40—52.
11. Polyhraf REOKOM STRESS / Naukovo-tekhnichnyi tsentr radioelektronnoho medychnoho obladnannia i tekhnolohii «KhAI-Medyka». URL: https://hai-medika.prom.ua/p358078095-poligraf-reokom-stress.html.
12. Zung, W. W. A self-rating depression scale // Archives of General Psychiatry. 1965. No. 12. P. 63—70.
13. Smulevich A. B. Depressii v obschey meditsine : rukovodstvo dlya vrachey. M.: Meditsinskoe informatsionnoe agentstvo, 2001. 782 s.
14. Zigmond A. S., Snaith R. P. The hospital anxiety and depression scale // Acta Psychiatrica Scandinavica. 1983. Vol. 67. No. 6. P. 361—370. DOI: 10.1111/j.1600-0447.1983.tb09716.x.
15. Kryilov A. A., Manichev S. A. Praktikum po obschey eksperimentalnoy i prikladnoy psihologii : ucheb. posobie. SPb. : Piter, 2000. 560 s.
16. AUDIT : the Alcohol Use Disorders Identification Test : guidelines for use in primary health care / [T. F. Babor, J. C. Higgins-Biddle, J. B. Saunders, M. G. Monteiro]. 2nd ed. World Health Organization. URL: https://apps.who.int/iris/handle/10665/67205.
17. Derogatis L. R., Savitz, K. L. The SCL-90-R and the Brief Symptom Inventory (BSI) in Primary Care. In : Handbook of psychological assessment in primary care settings / M. E. Maruish (Ed.). Mahwah, NJ : Lawrence Erlbaum Associates Publishers, 2000. P. 297—334.
18. Tarabrina N. V. Praktikum po psihologii posttravmaticheskogo stressa. SPb. : Piter. 2001. 272 s.
19. Gubler E. V. Vyichislitelnyie metodyi analiza i raspoznavaniya patologicheskih protsessov. M.: Meditsina, 1978. 294 s.
20. Lapach S. N., Chubenko A. V., Babich P. N. Statisticheskie metodyi v mediko-biologicheskih issledovaniyah s ispolzovaniem Excel. Kiev : «MorIon», 2000. 320 s.