ГоловнаArchive of numbers2014Volume 22, issue 3 (80)The eff ectiveness of surgical treatment of symptomatic epilepsy caused by cerebral cavernomas
Title of the article The eff ectiveness of surgical treatment of symptomatic epilepsy caused by cerebral cavernomas
Authors Tsymbaliuk Vitalii
Kostiuk Mykhailo Romanovych
Kostiuk Kostiantyn Romanovych
In the section MATERIALS OF 18TH ANNUAL CONFERENCE OF THE UKRAINIAN LEAGUE OF AGAINST EPILEPSY
Year 2014 Issue Volume 22, issue 3 (80) Pages 154-157
Type of article Scientific article Index UDK 616.853-089.168:616.831-006.311.03 Index BBK -
Abstract Cerebral cavernomas is an increasingly recognised cause of symptomatic epilepsy. The purpose of study is to assess the effi ciency of surgical treatment of symptomatic epilepsy in patients with cerebral cavernomas. 42 patients were enrolled in study, among them 24 (57.1 %) underwent surgery. Operating patients were divided on two groups. Group 1 inclu ded 10 patients with cavernomas in the temporal lobe. In this group 3 (30.0 %) patients underwent lesionectomy and in 7 (70.0 %) cases cavernoma’s resection was added anterior temporal lobectomy. Group 2 consists 14 patients with extratemporal lesion’s localization. Postoperative follow—up was from 1 to 3.5 years (mean — 2.4 years). In group 1 7 patients (70.0 %) became seizure-free or have rare seizures, in 3 (30.0 %) cases seizure frequency reduced slightly or did not change. Control for seizures was most eff ective in patients who underwent topectomy with additional anterior temporal lobectomy. In group 2 seizure control or significant seizure reduction was achieved in 7 (50.0 %) patients, in other 7 (50.0 %) cases seizure frequency reduced slightly or did not change. Surgical resection of lesion with additional excision of the hemosiderin- stained tissue improves control of seizures due to cerebral cavernomas. In temporal cavernomas such lesion resection should be supplemented by anterior temporal lobectomy. Duration of epilepsy before surgery and localisation of cavernoma seem to be important factors in seizure outcome after surgery.
Key words symptomatic epilepsy, seizures, cerebral cavernoma, anterior temporal lobectomy, topectomy
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