ГоловнаArchive of numbers2017Volume 25, issue 4 (93)The eff ectiveness of Cogniphen usage in the complex therapy of a craniocerebral trauma
Title of the article The eff ectiveness of Cogniphen usage in the complex therapy of a craniocerebral trauma
Authors Grygorova Iryna
Teslenko Olga
Grygorov Mykola
Year 2017 Issue Volume 25, issue 4 (93) Pages 59-65
Type of article Scientific article Index UDK 616.831-001.31-036.66-08 Index BBK -
Abstract Rehabilitation of patients with sequelae of craniocerebral trauma (CCT) is one of the most important medical and social problems of Ukraine today. Improvement of methods of the head injury treatment is an important problem for a practical doctor. The paper presents the results of a survey of 60 patients who underwent the CCT of the moderate severity in the long-term period. The study was performed in three stages as follows: on the day of admission of patients to the hospital, in 1 and 3 months against a background of complex therapy with the use of cogniphen (the main group) and pyracetam (control group). The effectiveness of therapy was assessed using psychodiagnostic scales, as well as the dynamics of neurological status and neuropsychological disorders. The results of the study show that the most pronounced eff ects of therapy were observed in patients of the main group with anxiety and anxiety-depressive disorders, depressive disorders with excitation, excessive irritability, tension, increased motor excitability and impaired spatial functions. In doing so, the improvement in the indicators of the psychoemotional sphere was noted already 1 month after the initiation of therapy with further stabilization. The usage of cogniphen in the complex therapy of the CCT quickly and signifi cantly improves the social adaptation of the injured patient.
Key words craniocerebral trauma, therapy, cogniphen
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Bibliography 1. Марков О. В. Хірургічна тактика при травматичних ушко- дженнях кісток черепа : автореф. дис. ... канд. мед. наук : спец. : 14.01.05 — Нейрохірургія / О. В. Марков ; НМАПО. Київ, 2007. 20 с. 2. Рахова Р. К., Раковлев Н. А. Клинико-психовегетативные и метаболи чес кие нарушения у больных с последствиями лег- кой черепно-мозговой травмы // Нейроиммунология. 2003. Т. 1, № 2. С. 124—125. 3. Бойко А. В., Костенко Е. В., Батышева Т. Т., Зайцев К. А. Череп но-мозговая травма // Consillium Medicum. 2007. Т. 9, № 8. С. 5—10. 4. Traumatic injury to the immature brain results in progressive neuronal loss, hyperactivity and delayed cognitive impairments / Pullela R., Raber J., Pfankuch T. [et al.] // Dev. Neurosci. 2006. Vol. 28. P. 396—409. 5. Захаров В. В, Дроздова Е. А. Когнитивные нарушения у боль ных с черепно-мозговой травмой // Неврология, нейро- пси хиат рия, психосоматика. 2013. Т. 4. С. 88—93. 6. Захаров В. В., Яхно Н. Н. Синдром умеренных когнитивных нарушений в пожилом возрасте: диагностика и лечение // РМЖ. 2004. № 10. С. 573. 7. Differential evolution of cognitive impairment in nondemented older persons: results from the Kungsholmen Project / Palmer K., Wang H.-X., Backman L. [et al.] // Am J Psychiatry. 2002. Vol. 159 (3). P. 436—42. 8. Norris C. M., Scheff S. Recovery of afferent function and synaptic strength in hippocampal CA1 following traumatic brain injury // J. Neurotrauma. 2009. Vol. 26, No. 12. P. 2269—2278.