ГоловнаArchive of numbers2017Volume 25, issue 3 (92)Pattern of antiepileptic drug prescription in children living in Kharkiv-city and region
Title of the article Pattern of antiepileptic drug prescription in children living in Kharkiv-city and region
Authors Dubenko Andrij
Tantsura Lyudmyla
Shatillo Andrii
Year 2017 Issue Volume 25, issue 3 (92) Pages 111-114
Type of article Scientific article Index UDK 616.853-053.2:615.213:477.54-083.8 Index BBK -
Abstract The article presents data processing results concerning course and drug treatment of children living in Kharkiv-city and region. An analysis has been done by the help of comparison between register data and compatible data from other sources, i. e. pattern of antiepileptic drug (AED) usage and pharmacoresistance in patients from other regions of Ukraine, who were treated in INPN NAMS of Ukraine in the same time period, and analogous publication data from diff erent countries. General pharmacoresistance has been proposed to use as integral assessment index of treatment quality in epileptic patient population, analysis of diff erent calculation ways has been done. The results of registry analysis have shown that AED usage pattern in Kharkiv-city and region is close to the world’s one: valproates — 39.9 % (1st place), carbamazepine — 38.6 % (2nd place); different ways of pharmacoresistance assessments give an index about 20 %, that is less than conventional index, about 30 %, for general epileptic patient’s population, but very close to some publications’ data concerning pediatric population; a difference between pharmacoresistance index calculated from registry and from epileptologic specialized center is about 10 %, which gives a base for recommendation to reference patients with epilepsy debut to such centers as soon as possible.
Key words pediatric epilepsy, regis ter, antiepileptic drugs, pharmacoresistance
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